Impairment 2.8 Administration Information 3 DOSAGE FORMS AND STRENGTHSĥ.1 Hyponatremia 5.2 Anaphylactic Reactions and Angioedema 5.3 Cross Hypersensitivity Reaction to Carbamazepine 5.4 Serious Dermatological Reactions 5.5 Suicidal Behavior and Ideation 5.6 Withdrawal of AEDs 5.7 Cognitive/Neuropsychiatric Adverse Reactions 5.8 Drug Reaction with Eosinophilia and Systemic Symptoms (įULL PRESCRIBING INFORMATION: CONTENTS * 1 INDICATIONS AND USAGEĢ.1 Adjunctive Therapy for Adults 2.2 Conversion to Monotherapy for Adults 2.3 Initiation of Monotherapy for Adults 2.4 Adjunctive Therapy for Pediatric Patients (Aged 2 to 16 Years) 2.5 Conversion to Monotherapy for Pediatric Patients (Aged 4 to 16 Years) 2.6 Initiation of Monotherapy for Pediatric Patients (Aged 4 to 16 Years) 2.7ĭosage Modification for Patients with Renal Initiation of Monotherapy for Patients (Aged 4 to 16 Years): Increments of 5 mg/kg/day every third day.Conversion to Monotherapy for Patients (Aged 4 to 16 Years): Maximum increment of 10 mg/kg/day at weekly intervals, concomitant antiepileptic drugs can be completely withdrawn over 3 to 6 weeks.For patients aged 2 to <4 years, maximum maintenance dose should be achieved over 2 to 4 weeks and should not to exceed 60 mg/kg/day. Adjunctive Patients (Aged 2 to 16 Years): For patients aged 4 to 16 years, target maintenance dose should be achieved over 2 weeks (Ģ.4).Recommended daily dose is dependent upon patient weight. For patients aged 2 to <4 years and under 20 kg, a starting dose of 16 to 20 mg/kg/day may be considered. Pediatrics: initiation with 8 to 10 mg/kg/day, given twice-a-day. Initiate at one-half the usual starting dose and increase slowly in patients with a creatinine clearance Initiation of Monotherapy: Increments of 300 mg/day every third day to a dose of 1,200 mg/day.Conversion to Monotherapy: withdrawal concomitant over 3 to 6 weeks reach maximum dose of oxcarbazepine oral suspension in 2 to 4 weeks with increments of 600 mg/day at weekly intervals to a recommended daily dose of 2,400 mg/day.The recommended daily dose is 1,200 mg/day. Adjunctive Therapy: Maximum increment of 600 mg/day at approximately weekly intervals.Adults: initiate with a dose of 600 mg/day, given twice-a-day

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